Advances in Biochips <p><a title="Registered Journal" href="" target="_blank" rel="noopener"><img src="/journal/public/site/images/jasongong/Logo_ReviewerCredits-journal.jpg" alt="" width="17%" align="right"></a><strong>Advances in Biochips (AB)</strong> (ISSN:2630-4511) is an open access, continuously published, international, refereed&nbsp; journal to show new ideas and optimize methods of this promising technology. With a broad range of disciplines and expanding topics, this journal encourages submissions of original research, review article, commentary, perspective, opinion, and so on.</p> <p>Topics of interest include, but are not limited to the following:<br>--Disease diagnosis<br>--Detection of bio agents<br>--DNA microarray<br>--Protein array<br>--Cell chip<br>--Tissue microarray<br>--Organ-on-a-chip<br>--Lab-on-a-chip<br>--Sequencing technology<br>--Chemical compound microarray<br>--Biosensor<br>--Microfluidics</p> en-US <p>Authors contributing to&nbsp;<em>Advances in Biochips</em>&nbsp;agree to publish their articles under the&nbsp;<a href="">Creative Commons Attribution-Noncommercial 4.0 International License</a>, allowing third parties to share their work (copy, distribute, transmit) and to adapt it, under the condition that the authors are given credit, that the work is not used for commercial purposes, and that in the event of reuse or distribution, the terms of this license are made clear.</p> (Alan Tan) (Snowy Wang) Fri, 30 Apr 2021 00:00:00 +0800 OJS 60 A reliable electrochemical sensor developed based on ZnO/SnO₂ nanoparticles modified glassy carbon electrode <p>The 4-NPHyd (4-nitrophenylhydrazine) electrochemical sensor assembled using wet-chemically prepared ZnO/SnO<sub>2</sub> nanoparticle (NPs) decorated a glassy carbon electrode (GCE) with conductive Nafion binder. The synthesized NPs characterized by XPS, ESEM, EDS, and XRD analysis. The calibration of the proposed sensor obtained from current versus concentration of 4-NPHyd found linear over a concentration (0.1 nM ~ 0.01 mM) of 4-NPHyd, which denoted as the dynamic range (LDR) for detection of 4-NPHyd. The 4-NPHyd sensor sensitivity calculated using the LDR slope considering the active surface of GCE (0.0316 cm<sup>2</sup>), which is equal to be 7.6930 µAµM/cm<sup>2</sup>, an appreciable value.&nbsp; The detection limit (LOD) at signal/noise (S/N = 3) estimated, and outstanding lower value at 94.63±4.73 pM perceived. The analytical parameters such as reproducibility, long-term performing ability and response time are found as appreciable. Finally, the projected sensor shows exceptional performances in the detection of 4-NPHyd in environmental samples.</p> M. Mahmud Alam, M. T. Uddin, Mohammed M. Rahman, Abdullah M. Asiri, M. A. Islam ##submission.copyrightStatement## Thu, 01 Jul 2021 00:00:00 +0800 Roles of polymer brushes in biological applications <p>Polymer brushes are macromolecular structures with polymer chains tethered to a surface resembling a brush. They have shown variety of uses in biological applications. Because of the nature of crafted polymers, the functionalized surfaces exhibit unique functions such as low friction, altered adhesion, protein binding and selective adsorption. Functionalization can be controlled by changing parameters such as grafting densities, chemical configurations, shapes and thickness. In this review, a particular emphasis has been provided for studies related to biological applications of polymer brushes based on their ultra-low friction, hydrophilic elongated surfaces, and binding properties. It provides useful information for researches and labs working on finding better solutions for drug delivery, arthritis, artificial joints, antibiofouling coatings and protein immobilization and purification.</p> Ajinkya Raut, Peter Renner, Rick Wang, Serge Kazadi, Siddhi Mehta, Yan Chen, Hong Liang ##submission.copyrightStatement## Fri, 30 Apr 2021 13:54:05 +0800