Pál Perjési, Institute of Pharmaceutical Chemistry, University of Pécs, Pécs, Hungary
Education
• M.S. Pharmacy, University Medical School of Szeged, Szeged, Hungary, 1979.
• Univ.D. Pharmaceutical Chemistry, University Medical School of Szeged, Hungary, 1983. Thesis: Synthesis of isoquinoline derivatives with potentially pharmacological activities.
• Candidate of Sciences Chemistry, Hungarian Academy of Sciences, Budapest, 1994. Thesis: Investigations on cyclization reactions of 2-arylideneketones to form 1,3-thiazine and pyrimidine derivatives.
• Ph.D. Habilitation Pharmaceutical Chemistry, University of Szeged, Szeged, Hungary, 1996; Chemistry, University of Pecs, Pecs, Hungary, 2000.
• Specialization Certificates Preparative chemical laboratory investigations Medical University of Advanced Studies, Budapest, Hungary, 1985; Toxicology Medical University of Advanced Studies, Budapest, Hungary, 1994.
Professional experience
• 1979-1981 Postgraduate Fellow, Institute of Pharmaceutical Chemistry, University Medical School, Szeged, Hungary.
• 1981-1993 Assistant Professor, Department of Medical Chemistry, University Medical School, Pecs, Hungary.
• 1990-1991 (12 months) Fogarty Fellow, Department of Medicinal Chemistry, University of Washington, Seattle, WA, U.S.A.
• 1993-1999 Senior Lecturer, Department of Medical Chemistry, University Medical School, Pecs, Hungary.
• 1999-2001 Associate Professor, Department of Medical Chemistry, University Medical School, Pecs, Hungary.
• 2001 (12 months) Postdoctoral Research Associate, Center for Drug Discovery, University of Florida, Gainesville, FL, U.S.A.
• 2002-2010 Associate Professor, Head of Institute, Institute of Pharmaceutical Chemistry, University Medical School, Pecs, Hungary.
• 2003 (3 months) Postdoctoral Research Associate, Department of Medicinal Chemistry, University of Florida, Gainesville, FL, U.S.A.
• 2009-2015 Head of School of Pharmacy, University of Pecs, Pecs, Hungary.
• 2010- Professor, Head of Institute, Institute of Pharmaceutical Chemistry, University Medical School, Pecs, Hungary.
• 2012 (3 months) Senior DAAD Fellow, University of Bonn, Kekulé-Institute of Organic Chemistry and Biochemistry, Bonn, Germany.
• 2016- Head of Faculty of Pharmacy, University of Pecs, Pecs, Hungary.
Research activities
• Synthesis, synthetic application and structural (UV, IR, NMR) investigation of chalcones and cyclic chalcone analogues (2-benzylidenecyclanones and 2-benzylidenebenzocyclanones) and their ferrocenyl counterparts.
• Structure-activity relationship studies on the effects of chalcones and cyclic chalcone analogues on the cell cycle of cancer cell lines.
• Structure-activity relationship studies on the antioxidant/prooxidant effects of chalcones, estrogens and non-steroidal anti-inflammatory drugs.
• Study on (stereo)chemistry of reaction of alfa,beta-unsaturated carbonyl compounds (chalcones, and cyclic chalcone analogues) with sulphur and nitrogen nucleophilic reagents.
• Investigation of biotransformation of capsaicinoids and non-steroidal anti-inflammatory drugs in the small intestine using ex vivo rat model.
• Chemico-biochemical backgrounds of cancer chemoprevention.
Publications Summary (MTMT.HU)
• Number of publications: 104
• Number of referred abstracts: 154
• Independent citations: 787
• Hirsch-index: 19
