Journal of Pharmaceutical and Biopharmaceutical Research

Objective: To explore and analyze the analgesic and arresting bleeding effects of Curcuma aromatica Salisb.
Methods: The aqueous extract and alcoholic extract with the analgesic and arresting bleeding effects come from the rhizome of C. aromatica. These effects can be analyzed by writhes of the abdominal cavity on mice, hot-plate test, bleeding time by cutting the mouse′s tail and recovery time of decalcifying plasma clotting.
Results: The aqueous extract and alcoholic extract of the rhizome of C. aromatica can effectively inhibit the writhing reaction of mice, and the effect intensity is similar. The high-dose group (10g/kg) of aqueous extract solution of C. aromatica could significantly shorten the bleeding time by cutting the mouse′s tail and the recovery time of decalcifying plasma clotting. There was a significant difference in pain by heat stimulation on mice before and after aqueous extract and alcoholic extract (P < 0.05).
Conclusion: The Curcuma aromatica has analgesic and arresting bleeding effects. The arresting bleeding effect is related to blood coagulation factors, and hemostatic activity is water-soluble.

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