Advances in General Practice of Medicine (ISSN:2529-8127) is an open access, continuously published, international, refereed  journal to promote comprehensive, coordinated and continuing care for the community members. This journal encourages submissions of original research, review article, clinical case study, clinical trial, commentary, perspective, opinion in the field addressed.

Topics of interest include, but are not limited to, the following:
 • Medical education and training
 • Medical management and evaluation
 • Clinical research
 • Health policy and guideline development
 • Whole person care
 • Health economics
 • International experiences and evolutions
 • Family doctor service model
 • Diagnostic and therapeutic
 • Basic medicine system
 • Health information technologies

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Advances in General Practice of Medicine (AGPM) is indexed by Google Scholar, Baidu Scholar, CQVIP, CNKI, and being indexed by other authoritative academic databases is under application.

Vol 3 No 1 (2020)

Published: 2020-11-02

Abstract views: 783   PDF downloads: 388  

Page 19-22

Acute renal failure as severe malaria complication in Lubumbashi: Management and follow-up in an under-equipped setting

blankpage Deddy C. Kalonji, Lebrun N. Kembo, Matthieu I. Ngombe, Stéphanie L. Ngimbi, Alex K. Lumande, Eva K. Bukasa, Patient N. Mudait, Olivier Mukuku, Augustin M. Mutombo, Michel N. Kabamba, André K. Mutombo, Stanislas O. Wembonyama, Oscar N. Luboya

Purpose Acute renal failure (ARF) or acute kidney injury (AKI) is one of the major criteria for the severity of malaria according to WHO. The objective was to determine the frequency as well as to evaluate the management and follow-up of ARF during malaria in children in Lubumbashi. Material and methods This is a descriptive cross-sectional study over 48 months (January 1st, 2016 to December 30th, 2019) carried out at the pediatric service of the University Clinics of Lubumbashi. All children with an ARF with a positive thick blood smear were included in the study. Data were analyzed with SPSS 19 software. Results During this period, 910 patients (49.1%) were admitted for malaria. Among them, 14 patients, i.e. an intra-hospital prevalence of 0.78%, of which 6 boys (42.9%) and 8 girls (57.1%) had ARF. The mean age is 7.9±3.5 years. The serum creatinine level was between 0.54 and 15.2 mg/dL with a mean of 5.7 mg/dL. Kidney dialysis was only effective in 3 patients (21.4%) and diuretics were given 100% in all children. The mean length of stay was 13.4±8.7 days (range: 1 day and 18 days). Mortality was 21.4%. Conclusion The present study shows that ARF in childhood malaria in Lubumbashi is infrequent but of high mortality in our environment with limited resources where care is lacking and monitoring difficult.

Abstract views: 847   PDF downloads: 408  

Pages 23-25

Cryptococcus neoformans meningitis in an immunocompetent adult: A case report

blankpage Georges Yumba Numbi, Berthe Kamalo Mwad, Olivier Mukuku, Claude Mulumba Mwamba

Neuromeningeal cryptococcosis (NMC) is relatively rare in immunocompetent subjects. We report a Congolese case of NMC diagnosed in an apparently immunocompetent subject. A 35-year-old woman was admitted for acute meningoencephalitis. The cerebrospinal fluid (CSF) examination revealed cytological and biochemical abnormalities and the presence of Cryptococcus neoformans on direct examination with India ink and in culture. The serum dosage of cryptococcal antigens was titrated at 1:32. HIV and syphilis antibodies were negative and the blood CD4 lymphocyte count was 610/mm3. The patient had no other immunosuppressive factors, in particular no hematologic abnormalities, no solid tumor, or malnutrition. She was unsuccessfully treated with fluconazole intraveinously, and died after 10 days of treatment. This observation reminds us that NMC can occur in subjects without apparent immunosuppressive factor with a misleading clinical presentation. It is a rare infection with a severe prognosis even in immunocompetent patients.

Abstract views: 724   PDF downloads: 426  

Pages 26-27

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Pietro Vajro-photo  ISSN: 2529-8127
 Abbreviation: Adv Gen Pract Med
 Editor-in-Chief: Prof. Pietro Vajro (Italy)
 Publishing Frequency: Continuous publication
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 Publishing Model:
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