Aims and Scope

ReviewerCreditsAdvances in General Practice of Medicine (AGPM) (ISSN:2529-8127) is an open access, continuously published, international, refereed  journal to promote comprehensive, coordinated and continuing care for the community members. This journal encourages submissions of original research, review article, clinical case study, clinical trial, commentary, perspective, opinion in the field addressed.

Topics of interest include, but are not limited to, the following:
• Medical education and training
• Medical management and evaluation
• Clinical research
• Health policy and guideline development
• Whole person care
• Health economics
• International experiences and evolutions
• Family doctor service model
 • Diagnostic and therapeutic
• Basic medicine system
• Health information technologies

Vol 5 No 1 (2023)

Published: 2023-03-02

Abstract views: 478   PDF downloads: 121  

Page 90-96

Predictors of in-hospital mortality among patients with status epilepticus in Lubumbashi, Democratic Republic of the Congo: A retrospective study

blankpage Marcellin Bugeme, Olivier Mukuku, Lucien Nawej Ditend, Emmanuel Kiyana Muyumba, Béatrice Koba Bora

Objective: Status Epilepticus (SE) is a condition characterized by an epileptic seizure that persists long enough or recurs at sufficiently short intervals to create a fixed and lasting epileptic condition. The objective of this study was to determine the prevalence and to identify predictors of in-hospital death among SE patients in Lubumbashi, Democratic Republic of the Congo (DRC).
Methods: We conducted a retrospective study from January 2020 to December 2022.
Results: Out of 3,006 patients admitted to the neurology department of the University Clinics of Lubumbashi, 97 presented with SE (i.e., a hospital prevalence of 3.23%). The mean age of the patients was 38.38±14.74 years, and men represented 77.3% of the cases. Epileptic patients represented 21.65% of the cases and 66.7% of them were on antiepileptic drugs (AEDs). Seizures were generalized in 72.16% of the patients. Seizures lasted 30 minutes or more in 50.52% of the cases. The most frequent etiologies were strokes, followed by central nervous system (CNS) infections. In-hospital mortality was 24.74% and the predictors of this mortality were CNS infections (adjusted OR = 22.34 [2.69-222.65]; p = 0.0006) and seizures lasting ≥ 30 minutes (adjusted OR = 10.98 [2.89-62.70]; p<0.0001).
Conclusion: SE is a major neurological emergency requiring early and multidisciplinary management to preserve the vital prognosis because, without treatment, SE causes important neurological complications and even death. The present study found a mortality of 24.74% which was associated with seizure duration of more than 30 minutes as well as with infectious etiologies.

Abstract views: 546   PDF downloads: 180  

Page 81-89

Prediction of mortality in adult COVID-19 patients using chest CT severity scoring systems: A comparative analysis of different scores

blankpage Didier Ndyanabo Ndabahweje, Olivier Mukuku, Charles Kangitsi Kahindo, Michel Lelo Tshikwela, Gertrude Luyeye Mvila, Antoine Molua Aundu, Jean Tshibola Mukaya, Stanis Okitotsho Wembonyama, Zacharie Kibendelwa Tsongo

Purpose: To compare the accuracy of mortality prediction of four CT severity scoring systems for COVID-19: CT severity score three levels, CT severity score, Total severity score, and Chest CT score.
Methods: This was a retrospective study of 278 patients hospitalized with COVID-19 confirmed by a positive polymerase chain reaction (PCR) and in whom a CT scan was performed to assess the severity of lung involvement. This assessment was performed using four different scoring systems, including the CT severity score three levels, the CT severity score, the Total severity score, and the Chest CT score.
Results: A total of 278 COVID-19 patients had chest CT scans, of whom 59 (21.22%) died and 219 (78.78%) survived. The ROC curves showed outstanding performance for the four chest CT severity scoring systems: 0.9580 for the CT severity score; 0.9532 for the CT severity score three levels; 0.9474 for the Total severity score; and 0.9327 for the Chest CT score. The comparison of these four ROC curves revealed no statistically significant difference between the four scoring systems (X2 = 3.89; p = 0.2740).
Conclusion: The four chest CT severity scoring systems used predicted mortality in COVID-19 patients with excellent agreement and outstanding performance.

Abstract views: 790   PDF downloads: 554  

Page 74-80

Prevalence and associated factors of uncontrolled hypertension in hypertensive patients in the city of Goma, DRC

blankpage Herman Ngadjole Chelo, Théophile Kabesha Barhwamire, Patricia Lukusa Mishika, Zacharie Kibendelwa Tsongo, Stanis Okitotsho Wembonyama

Background: The objectives of this study were to determine the proportion of uncontrolled hypertension in hypertensive patients followed up on an outpatient basis and to investigate the factors associated with this poor control.
Methods: This was a cross-sectional analytical study of 167 hypertensive patients followed in eight health facilities in Goma city. Uncontrolled hypertension was defined as systolic blood pressure (SBP) ≥140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg.
Results: The proportion of uncontrolled hypertension was 95.2%. In bivariate analysis, no factor was associated with uncontrolled hypertension.
Conclusion: Almost all hypertensive patients in our study were poorly controlled by antihypertensive treatment. These results highlight the need for a cohort study to determine the factors associated with this excessively high prevalence of uncontrolled hypertension in hypertensive patients on antihypertensive drugs, in order to allow targeted actions to try to control hypertension by antihypertensive drugs.

Abstract views: 23   PDF downloads: 10  

Page 97-101

Big challenge in health impact of heavy metal: A case study

blankpage Ritu Tiwari, Gaurav Sanjay Mahalpure

Herbal medicines are potential sources of therapeutic aids for human beings. WHO estimates that 80% of the world’s population depends on herbal products as their primary form of health care. Herbal plants are widely used nowadays because they have few side effects, are readily available, and are cost-effective. Herbal plants are easily contaminated by absorbing heavy metals from soil, air and water. The primary health concerns of heavy metals are Arsenic, Cadmium, Lead and Mercury.   Heavy metal causes countless health-related issues, such as kidney and liver damage, skin cancer, etc. So, the estimation of heavy metals is fundamental. Modern techniques estimate heavy metals in herbal plants such as AAS, ICP-MS, ICP-AES and ICP-OES. This review article mainly contains general information about heavy metals, the health impact of heavy metals on the human body, case studies regarding heavy metal toxicity on human health and analytical techniques used to estimate heavy metals.

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Pietro Vajro-photo  ISSN: 2529-8127
 Abbreviation: Adv Gen Pract Med
 Editor-in-Chief: Prof. Pietro Vajro (Italy)
 Publishing Frequency: Continuous publication
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 Publishing Model:
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