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Hematogone hyperplasia is seen in many reactive and neoplastic conditions such as autoimmune cytopenia(s), post viral infections, Hodgkin/ Non Hodgkin lymphoma, acute myeloid leukaemia, post chemotherapy or stem cell transplant bone marrow. However, occasionally a marked reactive process like hematogone hyperplasia can mask an important underlying morphology. It is further compounded in cases where the diagnostic cells are few in number. Clinching a diagnosis in such cases becomes increasingly difficult.
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