Open Access Peer-reviewed Case Report

Three first cases of Meige syndrome in Central Africa

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Marcellin Bugeme
Yacouba Kaba
Franck Shongo Omanjelo
Jacques Mbaz Musung
Sarah Kilumba Numbi
Olivier Mukuku corresponding author
Emmanuel Kiyana Muyumba
Dirk E. Teuwen


Meige syndrome (MS) is a rare type of focal dystonia characterized by unintentional bilateral activity in facial and mandibular muscles in combination with blepharospasm (spasm in the orbicular muscle). Often unknown cause, MS can be primary (idiopathic) or secondary (to medications or brain degenerative pathologies). Its treatment is based in most cases on botulinum toxin injections, not available in our environment. Nevertheless, clonazepam treatment has allowed us to improve the symptoms of our patients. We report MS in three patients, all with no particular history of consulting for involuntary facial movements. The diagnosis of MS was essentially based on the clinical picture. After treatment with clonazepam, the clinical course in all three patients was marked by the almost complete disappearance of these abnormal movements. In all cases, clinical progress was favorable with an average decline of 12 months; no recidivism was noted.

Meige syndrome, abnormal movements, clonazepam, Lubumbashi

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How to Cite
Bugeme, M., Kaba, Y., Omanjelo, F. S., Musung, J. M., Numbi, S. K., Mukuku, O., Muyumba, E. K., & Teuwen, D. E. (2022). Three first cases of Meige syndrome in Central Africa. Advances in General Practice of Medicine, 4(1), 67-70.


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