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Morphological stability of worm-like vesicles consisting of amphiphilic diblock copolymer against external stress

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Submitted   Apr 25, 2019
Published   May 28, 2019
Issue    Vol 1 No 2 (2019)
DOI   10.25082/CR.2019.02.006

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Eri Yoshida corresponding author
Department of Applied Chemistry and Life Science, Toyohashi University of Technology, 1-1 Hibarigaoka, Tempaku-cho, Toyohashi, Aichi 441-8580, Japan

Abstract

The morphological stability of vesicles consisting of an amphiphilic poly(methacrylic acid)-block-poly(methyl methacrylate-random-methacrylic acid) diblock copolymer, PMAA-b-P(MMA-r-MAA), was investigated against the external stresses of pH, salt concentration and polyamine.  The worm-like vesicles underwent a partial fusion at pH 12, however, they retained the worm-like shape at pH 13 due to electrostatic repulsion.  On the other hand, the spherical vesicles were completely fused at pH 12, transformed into a sheet and did not retain their shape under the higher basic condition.  Similarly, the worm-like vesicles retained their morphology in 0.1-mol% solutions of sodium chloride and sodium dodecyl sulfate, while the spherical vesicles caused division and fusion even at much lower concentrations.  Poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) transformed the worm-like vesicle into a cleavable sheet, while it changed the spherical vesicles into a sheet without a specific form.  It was found that this transformation based on the acid-base interaction between the carboxylic acid of the MAA block and the amine of the PDMAEMA was dependent on the molecular weight of the PDMAEMA.  The short PDMAMA retarded the fusion of the vesicles.

Keywords
morphological stability, external stresses, worm-like vesicles, spherical vesicles, amphiphilic diblock copolymer, polyamine

Article Details

How to Cite
Yoshida, E. (2019). Morphological stability of worm-like vesicles consisting of amphiphilic diblock copolymer against external stress. Chemical Reports, 1(2), 102-107. https://doi.org/10.25082/CR.2019.02.006
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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