Advances in Biochips (AB) (ISSN:2630-4511) is an open access, continuously published, international, refereed  journal to show new ideas and optimize methods of this promising technology. With a broad range of disciplines and expanding topics, this journal encourages submissions of original research, review article, commentary, perspective, opinion, and so on.

Topics of interest include, but are not limited to the following:
--Disease diagnosis
--Detection of bio agents
--DNA microarray
--Protein array
--Cell chip
--Tissue microarray
--Organ-on-a-chip
--Lab-on-a-chip
--Sequencing technology
--Chemical compound microarray
--Biosensor
--Microfluidics


Vol 2 No 1 (2021)

Published: 2021-04-30

Abstract views: 362   PDF downloads: 167  
2021-07-01

Page 24-34

A reliable electrochemical sensor developed based on ZnO/SnO₂ nanoparticles modified glassy carbon electrode

blankpage M. Mahmud Alam, M. T. Uddin, Mohammed M. Rahman, Abdullah M. Asiri, M. A. Islam

The 4-NPHyd (4-nitrophenylhydrazine) electrochemical sensor assembled using wet-chemically prepared ZnO/SnO2 nanoparticle (NPs) decorated a glassy carbon electrode (GCE) with conductive Nafion binder. The synthesized NPs characterized by XPS, ESEM, EDS, and XRD analysis. The calibration of the proposed sensor obtained from current versus concentration of 4-NPHyd found linear over a concentration (0.1 nM ~ 0.01 mM) of 4-NPHyd, which denoted as the dynamic range (LDR) for detection of 4-NPHyd. The 4-NPHyd sensor sensitivity calculated using the LDR slope considering the active surface of GCE (0.0316 cm2), which is equal to be 7.6930 µAµM/cm2, an appreciable value.  The detection limit (LOD) at signal/noise (S/N = 3) estimated, and outstanding lower value at 94.63±4.73 pM perceived. The analytical parameters such as reproducibility, long-term performing ability and response time are found as appreciable. Finally, the projected sensor shows exceptional performances in the detection of 4-NPHyd in environmental samples.

Abstract views: 630   PDF downloads: 272  
2021-04-30

Page 12-23

Roles of polymer brushes in biological applications

blankpage Ajinkya Raut, Peter Renner, Rick Wang, Serge Kazadi, Siddhi Mehta, Yan Chen, Hong Liang

Polymer brushes are macromolecular structures with polymer chains tethered to a surface resembling a brush. They have shown variety of uses in biological applications. Because of the nature of crafted polymers, the functionalized surfaces exhibit unique functions such as low friction, altered adhesion, protein binding and selective adsorption. Functionalization can be controlled by changing parameters such as grafting densities, chemical configurations, shapes and thickness. In this review, a particular emphasis has been provided for studies related to biological applications of polymer brushes based on their ultra-low friction, hydrophilic elongated surfaces, and binding properties. It provides useful information for researches and labs working on finding better solutions for drug delivery, arthritis, artificial joints, antibiofouling coatings and protein immobilization and purification.

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Zhenqing Li-photo  ISSN: 2630-4511
 Abbreviation: Adv Biochips
 Editor-in-Chief: Prof. Zhenqing Li(China)
 Publishing Frequency: Continuous publication
 Article Processing Charges (APC):
0
 Publishing Model:
Open Access