Open Access Peer-reviewed Research Article

Quality of life of people with epilepsy at a tertiary referral centre in Goma, in the DRC

Main Article Content

François Maheshe Polepole
Olivier Mukuku corresponding author
Franck Shongo Omangelo
Alfred Chasumba Murhula
Marcellin Bugeme
Théophile Barhwamire Kabesha
Stanis Okitotsho Wembonyama
Zacharie Kibendelwa Tsongo

Abstract

Purpose: This study aims to determine the quality of life (QOL) related to the health of people with epilepsy (PWE) followed in ambulatory care at the Neuropsychiatric Hospital Center in Goma, in the Democratic Republic of the Congo.
Methods:  A total of 302 adults with epilepsy followed in ambulatory care at the Neuropsychiatric Hospital Center in Goma were interviewed in this cross-sectional study. The QOL was measured using a validated French-language version of the Quality of Life in Epilepsy-31 inventory (QOLIE-31).
Results: The mean age was 28.4±11.0 years and 56.9% were males. The mean total QOLIE-31 score was 47.7±11.0. The highest subscale score was overall QOL with a mean of 57.5±15.0 and the lowest was medication effects with 39.7±27.5. Unemployment, presence of seizures, tobacco use, and co-morbidities (medical or psychiatric) significantly affected QOL (p < 0.05). All QOL subscales showed a significant correlation with seizure frequency, except for medication effects.
Conclusion: Worrying about seizures had the major contribution to QOL, while the medication effects had the least. This study confirms the importance of seizure control for better QOL in Congolese PWE.

Keywords
quality of life, epilepsy, QOLIE-31, Goma

Article Details

How to Cite
Polepole, F. M., Mukuku, O., Omangelo, F. S., Murhula, A. C., Bugeme, M., Kabesha, T. B., Wembonyama, S. O., & Tsongo, Z. K. (2022). Quality of life of people with epilepsy at a tertiary referral centre in Goma, in the DRC. Advances in Health and Behavior, 5(1), 226-232. https://doi.org/10.25082/AHB.2022.01.005

References

  1. Mukuku O, Nawej P, Bugeme M, et al. Epidemiology of epilepsy in Lubumbashi, Democratic Republic of Congo. Neurology Research International, 2020, 2020: 5621461. https://doi.org/10.1155/2020/5621461
  2. Fisher RS, Acevedo C, Arzimanoglou A, et al. Définition clinique pratique de l'épilepsie. Epilepsia, 2014, 55(4): 475-482. https://doi.org/10.1111/epi.12550
  3. Ville D. What's about new treatments in children epilepsy in 2010? Archives de Pédiatrie, 2010, 17(6): 688-690. https://doi.org/10.1016/S0929-693X(10)70061-0
  4. Ville D. L'épilepsie de l'enfant. Contraste, 2013, 38(2): 37-57. https://doi.org/10.3917/cont.038.0037
  5. Polepole FM, Mukuku O, Murhula AC, et al. Epidemiological and clinical features of epileptic patients in Goma, Democratic Republic of the Congo. Journal of the Neurological Stroke, 2022, 12(4): 84-88.
  6. World Health Organization (WHO). Epilepsy: Fact Sheet: World Health Organization, 2012. https://www.who.int/en/news-room/fact-sheets/detail/epilepsy
  7. Owolabi LF, Adamu B, Jibo AM, et al. Prevalence of active epilepsy, lifetime epilepsy prevalence, and burden of epilepsy in Sub-Saharan Africa from meta-analysis of door-to-door population-based surveys. Epilepsy & Behavior, 2020, 103: 106846. https://doi.org/10.1016/j.yebeh.2019.106846
  8. Bora K, Malamba D, Luwa DO, et al. Living with epilepsy in Lubumbashi (Democratic Republic of Congo): epidemiology, risk factors and treatment gap. The Pan African Medical Journal, 2015, 21: 303. https://doi.org/10.11604/pamj.2015.21.303.5580
  9. Ngugi AK, Bottomley C, Kleinschmidt I, et al. Estimation of the burden of active and life‐time epilepsy: a meta-analytic approach. Epilepsia, 2010, 51(5): 883-890. https://doi.org/10.1111/j.1528-1167.2009.02481.x
  10. Arborio S and Dozon JP. La dimension socioculturelle de l'épilepsie (kirikirimasien) en milieu rural Bambara (Mali). Bull Soc Pathol Exot Filiales, 2000, 93: 241-246.
  11. Gabriel MR, David LS and Peter R. Health-related quality of life in childhood epilepsy: Moving beyond 'seizure control with minimal adverse effects'. Health Qual Life Outcomes, 2003, 1: 36. https://doi.org/10.1186/1477-7525-1-36
  12. Kinyanjui DW, Kathuku DM and Mburu JM. Quality of life among patients living with epilepsy attending the neurology clinic at Kenyatta National Hospital, Nairobi, Kenya: a comparative study. Health Qual Life Outcomes, 2013, 11: 98. https://doi.org/10.1186/1477-7525-11-98
  13. Vickrey BG, Perrine KR, Hays RD, et al. Quality of life in epilepsy QOLIE-31 (Version 1.0): Scoring manual and patient inventory. Santa Monica, CA: Rand, 1993.
  14. Picot MC, Crespel A, Daurès JP, et al. Psychometric validation of the French version of the quality of life in epilepsy inventory (QOLIE-31): Comparison with a generic health-related quality of life questionnaire. Epileptic Disorders, 2004, 6(4): 275-285.
  15. Nubukpo P, Clement JP, Houinato D, et al. Psychosocial issues in people with epilepsy in Togo and Benin (West Africa) II: quality of life measured using the QOLIE-31 scale. Epilepsy & Behavior, 2004, 5(5): 728-734. https://doi.org/10.1016/j.yebeh.2004.07.002
  16. Norsa'adah B, Zainab J and Knight A. The quality of life of people with epilepsy at a tertiary referral centre in Malaysia. Health & Quality of Life Outcomes, 2013, 11(1): 143. https://doi.org/10.1186/1477-7525-11-143
  17. McLaughlin DP, Pachana NA and Mcfarland K. Stigma, seizure frequency and quality of life: the impact of epilepsy in late adulthood. Seizure, 2008, 17(3): 281-287. https://doi.org/10.1016/j.seizure.2007.09.001
  18. Guekht AB, Mitrokhina TV, Lebedeva AV, et al. Factors influencing on quality of life in people with epilepsy. Seizure, 2006, 16(2): 128-133. https://doi.org/10.1016/j.seizure.2006.10.011
  19. Altwijri RM, Aljohani MS and Alshammari HK. Quality of life among epileptic patients in Qassim Region, KSA. Neurosciences, 2021, 26(1): 56-61. https://doi.org/10.17712/nsj.2021.1.20200044
  20. Peterson CL, Walker C, Coleman H, et al. Reported service needs at diagnosis of epilepsy and implications for quality of life. Epilepsy & Behavior, 2019, 100(Pt A): 106527. https://doi.org/10.1016/j.yebeh.2019.106527
  21. Gu XM, Ding CY, Wang N, et al. Influence of Occupational Status on the Quality of Life of Chinese Adult Patients with Epilepsy. Chinese Medical Journal, 2016, 129(11): 1285-1290. https://doi.org/10.4103/0366-6999.182827
  22. Kubota H and Awaya Y. Assessment of health-related quality of life and influencing factors using QOLIE-31 in Japanese patients with epilepsy. Epilepsy & Behavior, 2010, 18: 381-387. https://doi.org/10.1016/j.yebeh.2010.04.045
  23. Djibuti M and Shakarishvili R. Influence of clinical, demographic, and socioeconomic variables on quality of life in patients with epilepsy: findings from Georgian study. Journal of Neurology Neurosurgery & Psychiatry, 2003, 74(5): 570-573. https://doi.org/10.1136/jnnp.74.5.570
  24. Herodes M, Oun A, Haldre S, et al. Epilepsy in Estonia: a quality-of-life study. Epilepsia, 2001, 42(8): 1061-1073. https://doi.org/10.1046/j.1528-1157.2001.0420081061.x
  25. Baker GA, Gagnon D and Mcnulty P. The relationship between seizure frequency, seizure type and quality of life: Findings from three European countries. Epilepsy Research, 1998, 30(3): 231-240. https://doi.org/10.1016/S0920-1211(98)00010-2
  26. Balogou AAK, Grunitzky EK, Belo M, et al. Management of epilepsy patients in Batamariba district, Togo. Acta Neurologica Scandinavica, 2007, 116: 211-216.
  27. Balogou AAK, Assogba K, Agbobli A, et al. Anxiété, dépression et qualité de vie des épileptiques en milieu urbain dans un pays en développement: le Togo. Epilepsies, 2010, 22(1): 79-83. https://doi.org/10.1684/epi.2010.0286