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Long-term survivors of advanced and metastatic lung cancer

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Clinical features of all patients
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Submitted   Aug 30, 2019
Published   Oct 5, 2019
Issue    Vol 1 (2019)
DOI   10.25082/CCR.2019.01.003

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Samira Mhamdi
Department of Pneumology, Military Hospital of Tunis, Mont Fleury 1008, Tunisia & Tunis Faculty of Medicine, Tunis El Manar University, Tunis 1007, Tunisia
Raana Fessi
Department of Pneumology, Military Hospital of Tunis, Mont Fleury 1008, Tunisia & Tunis Faculty of Medicine, Tunis El Manar University, Tunis 1007, Tunisia
Selsabil Daboussi
Department of Pneumology, Military Hospital of Tunis, Mont Fleury 1008, Tunisia & Tunis Faculty of Medicine, Tunis El Manar University, Tunis 1007, Tunisia
Abir Hedhli
Tunis Faculty of Medicine, Tunis El Manar University, Tunis 1007, Tunisia & Department of Pneumology, La Rabta Hospital, Tunis, Tunisia
Zied Moetamri
Department of Pneumology, Military Hospital of Tunis, Mont Fleury 1008, Tunisia & Tunis Faculty of Medicine, Tunis El Manar University, Tunis 1007, Tunisia
Chiraz Aichaouia
Department of Pneumology, Military Hospital of Tunis, Mont Fleury 1008, Tunisia & Tunis Faculty of Medicine, Tunis El Manar University, Tunis 1007, Tunisia
Mohsen Khadhraoui
Department of Pneumology, Military Hospital of Tunis, Mont Fleury 1008, Tunisia & Tunis Faculty of Medicine, Tunis El Manar University, Tunis 1007, Tunisia
Rezaig Cheikh
Department of Pneumology, Military Hospital of Tunis, Mont Fleury 1008, Tunisia & Tunis Faculty of Medicine, Tunis El Manar University, Tunis 1007, Tunisia
Salem Bouomrani corresponding author
Department of Internal medicine. Military Hospital of Gabes. Gabes 6000. Tunisia & Sfax Faculty of Medicine, University of Sfax. Sfax 3029, Tunisia

Abstract

The overall prognosis in patients with advanced and metastatic lung cancer is poor, however a subset of these patients has durable survival and they are called long-term survivors (LS). The definition of LS varies in published series from 18 months to 5 years. Few studies have focused on them. We report six cases of LS patients: three cases of non-small- cell lung cancer (stage IIIB and stage IV), two case of small cell lung cancer, and a case of composite carcinoma (small cell carcinoma and squamous carcinoma), all having a survival of five years or more. Our patients show clinical and evolutionary similarities with LS in the literature regarding the prognostic factors associated with prolonged survival namely performance status and good response to first-line chemotherapy.

Keywords
lung-cancer, stage III and IV, prognosis, chemotherapy, survivors

Article Details

How to Cite
Mhamdi, S., Fessi, R., Daboussi, S., Hedhli, A., Moetamri, Z., Aichaouia, C., Khadhraoui, M., Cheikh, R., & Bouomrani, S. (2019). Long-term survivors of advanced and metastatic lung cancer. Current Cancer Reports, 1(1), 13-19. https://doi.org/10.25082/CCR.2019.01.003
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