Open Access Peer-reviewed Editorial

Pharmacy, the continuously expanding field of science

Main Article Content

Pál Perjési corresponding author

Abstract

Originating from the traditional herbal formulations, nowadays, Pharmacy covers all the disciplines focusing on the behavior of complex pharmaceutical forms, drug-releasing systems, and active compounds in the human body. Masters of pharmaceutical sciences must know the basics of pharmaceutical chemistry, pharmaceutical technology, biotechnology, biology, physiology, pharmacology, and toxicology.

Article Details

Author Biography

Pál Perjési, Institute of Pharmaceutical Chemistry, University of Pécs, Pécs, Hungary

Education

M.S.  Pharmacy, University Medical School of Szeged, Szeged, Hungary, 1979.
Univ.D.   Pharmaceutical Chemistry, University Medical School of Szeged, Hungary, 1983. Thesis: Synthesis of isoquinoline derivatives with potentially pharmacological activities.
Candidate of Sciences   Chemistry, Hungarian Academy of Sciences, Budapest, 1994. Thesis: Investigations on cyclization reactions of 2-arylideneketones to form 1,3-thiazine and pyrimidine derivatives.
Ph.D. Habilitation   Pharmaceutical Chemistry, University of Szeged, Szeged, Hungary, 1996; Chemistry, University of Pecs, Pecs, Hungary, 2000.
Specialization Certificates  Preparative chemical laboratory investigations Medical University of Advanced Studies, Budapest, Hungary, 1985; Toxicology Medical University of Advanced Studies, Budapest, Hungary, 1994.

Professional experience

• 1979-1981 Postgraduate Fellow, Institute of Pharmaceutical Chemistry, University Medical School, Szeged, Hungary.
• 1981-1993 Assistant Professor, Department of Medical Chemistry, University Medical School, Pecs, Hungary.
• 1990-1991 (12 months) Fogarty Fellow, Department of Medicinal Chemistry, University of Washington, Seattle, WA, U.S.A.
• 1993-1999 Senior Lecturer, Department of Medical Chemistry, University Medical School, Pecs, Hungary.
• 1999-2001 Associate Professor, Department of Medical Chemistry, University Medical School, Pecs, Hungary.
• 2001 (12 months) Postdoctoral Research Associate, Center for Drug Discovery, University of Florida, Gainesville, FL, U.S.A.
• 2002-2010 Associate Professor, Head of Institute, Institute of Pharmaceutical Chemistry, University Medical School, Pecs, Hungary.
• 2003 (3 months) Postdoctoral Research Associate, Department of Medicinal Chemistry, University of Florida, Gainesville, FL, U.S.A.
• 2009-2015 Head of School of Pharmacy, University of Pecs, Pecs, Hungary.
• 2010- Professor, Head of Institute, Institute of Pharmaceutical Chemistry, University Medical School, Pecs, Hungary.
• 2012 (3 months) Senior DAAD Fellow, University of Bonn, Kekulé-Institute of Organic Chemistry and Biochemistry, Bonn, Germany.
• 2016- Head of Faculty of Pharmacy, University of Pecs, Pecs, Hungary.

Research activities

• Synthesis, synthetic application and structural (UV, IR, NMR) investigation of chalcones and cyclic chalcone analogues (2-benzylidenecyclanones and 2-benzylidenebenzocyclanones) and their ferrocenyl counterparts.
• Structure-activity relationship studies on the effects of chalcones and cyclic chalcone analogues on the cell cycle of cancer cell lines.
• Structure-activity relationship studies on the antioxidant/prooxidant effects of chalcones, estrogens and non-steroidal anti-inflammatory drugs.
• Study on (stereo)chemistry of reaction of alfa,beta-unsaturated carbonyl compounds (chalcones, and cyclic chalcone analogues) with sulphur and nitrogen nucleophilic reagents.
• Investigation of biotransformation of capsaicinoids and non-steroidal anti-inflammatory drugs in the small intestine using ex vivo rat model.
• Chemico-biochemical backgrounds of cancer chemoprevention.

Publications Summary (MTMT.HU)

• Number of publications: 104
• Number of referred abstracts: 154
• Independent citations: 787
• Hirsch-index: 19

How to Cite
Perjési, P. (2022). Pharmacy, the continuously expanding field of science. Journal of Pharmaceutical and Biopharmaceutical Research, 3(1), 185-186. https://doi.org/10.25082/JPBR.2021.01.003

References

  1. Perj´esi P. Pharmacy, the interdisciplinary field of science. Journal of Pharmaceutical and Biopharmaceutical Research, 2018, 1(1): 1-2. https://doi.org/10.25082/JPBR.2018.01.001
  2. Rodgers R, Austin C, Anderson J, et al. Glimmers in illuminating the druggable genome. Nature Reviews Drug Discovery, 2018, 17: 301-302. https://doi.org/10.1038/nrd.2017.252
  3. Santos R, Ursu O, Gaulton A, et al. A comprehensive map of molecular drug targets. Nature Reviews Drug Discovery, 2016, 16: 19-34. https://doi.org/10.1038/nrd.2016.230
  4. de la Torre BG and Albericio F. The pharmaceutical industry in 2019. An analysis of FDA drug approvals from the perspective of molecules. Molecules, 2020, 25(3): 745. https://doi.org/10.3390/molecules25030745
  5. Dammes N and Peer D. Paving the road for RNA therapeutics. Trends in Pharmacological Sciences, 2020, 41(10): 755-775. https://doi.org/10.1016/j.tips.2020.08.004
  6. Daley J. Gene therapy arrives. Nature, 2019, 576(7785): S12-S13. https://doi.org/10.1038/d41586-019-03716-9
  7. Damase TR, Sukhovershin R, Boada C, et al. The Limitless Future of RNA Therapeutics. Frontiers in Bioengineering and Biotechnology, 2021, 9: 628137. https://doi.org/10.1038/10.3389/fbioe.2021.628137
  8. DeWeerdt S. RNA therapies explained. Nature, 2019, 574: S2-S3. https://doi.org/10.1038/d41586-019-03068-4
  9. Dolgin E. The tangled history of mRNA vaccines. Nature, 2021, 597: 318-324. https://doi.org/10.1038/d41586-021-02483-w