Determination of pesticide residues and heavy metals in Adhatoda Vasaka Linn.
Main Article Content
Abstract
Heavy metals and pesticide residue analysis plays an important role in the quality control of medicinal plants like Vasaka (Adhatoda vasica). Hence a study was conducted to determine heavy metals and pesticide residues in this medicinal herb, which is a highly useful commodity in the health system. The reliable, rapid and nontoxic sample preparation method like QuEChERS and analytical methods like GC-MS were proposed for the simultaneous determination of pesticide residues and Heavy metal detection was carried out by ICP-MS. In this study, the presence of organophosphorus and organochlorine pesticides like alachlor, heptachlor, heptachlor epoxide, aldrin, dieldrin, endrin, etc was checked but not detected. Heavy metals like Arsenic (As), Cadmium (Cd), Mercury (Hg) and Lead (Pb) are traced in samples about 2.3005 ppb, 0.799 ppb, 2.290 ppb and 10.204 ppb respectively in the present study.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
References
- Jurca T, Marian E, Vicas L, et al. Analysis of metal content in herbal medicines. Rev Chim (Bucharest). 2013, 64(12): 1395-1398.
- Selvi C, Paramasivam M. Review on pesticide residue analytical methods and residue status in medicinal plants. Journal of Entomology and Zoology Studies. 2017, 5(3): 945-950.
- Shaban NS, Abdou KA, Hassan NEHY. Impact of toxic heavy metals and pesticide residues in herbal products. Beni-Suef University Journal of Basic and Applied Sciences. 2016, 5(1): 102-106. https://doi.org/10.1016/j.bjbas.2015.10.001
- Arunkumar S, Muthuselvam M. Analysis of phytochemical constituents and antimicrobial activities of Aloe vera L. against clinical pathogens. World Journal of Agricultural Sciences. 2009, 5(5): 572-576.
- Prakash J, Srivastava S, Ray RS, et al. Current Status of Herbal Drug Standards in the Indian Pharmacopoeia. Phytotherapy Research. 2017, 31(12): 1817-1823. https://doi.org/10.1002/ptr.5933
- Moreira D de L, Teixeira SS, Monteiro MHD, et al. Erratum on “Traditional use and safety of herbal medicines” [Rev. Bras. Farmacogn. 24(2014): 248-257]. Revista Brasileira de Farmacognosia. 2014, 24(4): 502-503. https://doi.org/10.1016/j.bjp.2014.09.002
- Gajalakshmi S, Iswarya V, Ashwini R, et al. Evaluation of heavy metals in medicinal plants growing in Vellore District. European Journal of Experimental Biology. 2012, 2(5): 1457-1461.
- Rehman A, Iqbal T, Ayaz S, et al. Investigations of heavy metals in different medicinal plants. Journal of Applied Pharmaceutical Science. 2013, 3(8): 72-74.
- Hong YS, Song KH, Chung JY. Health Effects of Chronic Arsenic Exposure. Journal of Preventive Medicine and Public Health. 2014, 47(5): 245-252. https://doi.org/10.3961/jpmph.14.035
- Leo MLN, Hamir SR. Handbook of pesticides, Methods of pesticide Residue Analysis. CRS Press. Chapter 15, 401-405.
- Zainudin BH, Salleh S, Mohamed R, et al. Development, validation and determination of multiclass pesticide residues in cocoa beans using gas chromatography and liquid chromatography tandem mass spectrometry. Food Chemistry. 2015, 172: 585-595. https://doi.org/10.1016/j.foodchem.2014.09.123
- Oh CH. Multi Residual Pesticide Monitoring in Commercial Herbal Crude Drug Materials in South Korea. Bulletin of Environmental Contamination and Toxicology. 2007, 78(5): 314-318. https://doi.org/10.1007/s00128-007-9176-9
- GUO Q, LV X, TAN L, et al. Simultaneous Determination of 26 Pesticide Residues in 5 Chinese Medicinal Materials Using Solid-phase Extraction and GC-ECD Method. Chinese Journal of Natural Medicines. 2009, 7(3): 210-216. https://doi.org/10.3724/sp.j.1009.2009.00210
- Tripathy V, Saha A, Patel DJ, et al. Validation of a QuEChERS-based gas chromatographic method for analysis of pesticide residues inCassia angustifolia(senna). Journal of Environmental Science and Health, Part B. 2016, 51(8): 508-518. https://doi.org/10.1080/03601234.2016.1170544
- Tripathy V, Saha A, Kumar J. Detection of pesticides in popular medicinal herbs: a modified QuEChERS and gas chromatography–mass spectrometry based approach. Journal of Food Science and Technology. 2017, 54(2): 458-468. https://doi.org/10.1007/s13197-017-2487-x
- Rao MM, KumarMeena A, Galib. Detection of toxic heavy metals and pesticide residue in herbal plants which are commonly used in the herbal formulations. Environmental Monitoring and Assessment. 2011, 181(1-4): 267-271. https://doi.org/10.1007/s10661-010-1828-2
- Sudha K, Bhavani C, Vivek C. Heavy metal analysis from traditionally used herb Ceropegia juncea (Roxb.) Journal of Pharmacy. 2014, 4(12): 07-11.
- Rajani M, Soni S, Anandjiwala S, et al. Validation of different methods of preparation of textitAdhatoda vasica leaf juice by quantification of total alkaloids and vasicine. Indian Journal of Pharmaceutical Sciences. 2008, 70(1): 36. https://doi.org/10.4103/0250-474x.40329
- Gangwar AK, Ghosh AK. Medicinal uses and Pharmacological activity of Adhatoda vasica. International Journal of Herbal Medicine. 2014, 2(1): 88-91.
- Rasdi F, Bakar N, Mohamad S. A Comparative Study of Selected Trace Element Content in Malay and Chinese Traditional Herbal Medicine (THM) Using an Inductively Coupled Plasma-Mass Spectrometer (ICP-MS). International Journal of Molecular Sciences. 2013, 14(2): 3078-3093. https://doi.org/10.3390/ijms14023078
- Schenck FJ, Hobbs JE. Evaluation of the Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) Approach to Pesticide Residue Analysis. Bulletin of Environmental Contamination and Toxicology. 2004, 73(1). https://doi.org/10.1007/s00128-004-0388-y
- Rutkowska E, Łozowicka B, Kaczyński P. Modification of Multiresidue QuEChERS Protocol to Minimize Matrix Effect and Improve Recoveries for Determination of Pesticide Residues in Dried Herbs Followed by GC-MS/MS. Food Analytical Methods. 2017, 11(3): 709-724. https://doi.org/10.1007/s12161-017-1047-3